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Several studies have reported pathological astrogliosis and associated neuronal hypotrophic glucose metabolism in patients with neurodegenerative disease and diabetic model animals, showing increased glial fibrillary acidic protein (GFAP) and significant cellular hypertrophy (32), which has been correlated to some extent with the severity of cognitive impairment in patients with Alzheimers disease (AD)

Sikiric et al., 2020b), to induce a simultaneous healing, even in different tissues (and therefore the healing of diverse fistulas (Klicek et al., 2008

It's important to emphasize: virtually all of this research has been conducted in animal models

Researchers must handle reconstituted peptides carefully because theyre more susceptible to hydrolysis and other forms of degradation