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Nuclear egress of TDP-43 and FUS occurs independently of exportin-1/CRM1

Therefore, a deeper understanding of the regulation, interactions with other metabolic pathways and mechanism of -PL biosynthesis, could facilitate a rational genetic approach, integrating high-throughput techniques, omics data and in silico models, and then provide extensive information on the regulatory and biosynthetic systems of -PL production and promote enhanced metabolic flux towards -PL biosynthesis [14]

Activity-based probes as a tool for functional proteomic analysis of proteases