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Herein, we will point out in evidence the relevance of some components of the TME, such as the angiogenic factors, the role of podoplanin (PDPN) in MB spreading, do not eat me signals, and the interaction between the astrocytes and MB cells ( Figure 5 )

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Additionally, in this group, a linear relationship existed between the observed change in CNFD and the change in symptoms for the ARA 290 subjects as assessed by PainDetect (Figure 6)