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And here is a paper about the involvement of the HGF/MET pathway (that is potentiated by dihexa) in brain tumours: Mulcahy, Elizabeth Qian Xu, Rossymar Rivera Coln, and Roger Abounader

Acta Pharm Sin 2(4):327334 Zhang Q, Piao X-L, Piao X-S, Lu T, Wang D, Kim SW (2011) Preventive effect of Coptis chinensis and Berberine on intestinal injury in rats challengedwith lipopolysaccharides