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However, at an early age, controlled leakage of the intestine may be necessary to trigger the development of immune system via hormetic mechanisms

On study day 0, all mice were inoculated with 1.25 10 4 PFU of SARS-CoV-2 Delta B.1.617.2 via intranasal instillation, a challenge dose determined from a previous study 80

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Oxyntomodulin Oxyntomodulin (OXM) is a 37-amino acid anorexigenic peptide hormone produced in the L-cells of the distal small intestine and colon, where it co-localizes with GLP-1 and PYY