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This review synthesizes evidence from randomized controlled trials and meta-analyses published up to 2024, evaluating the efficacy and safety of commonly used supplements such as myo-inositol, vitamin D, omega-3 fatty acids, selenium, and coenzyme Q10

HIF-1 perpetuates the interaction between synoviocytes and T and B cells, which in turn induces persistent production of inflammatory factors and autoantibodies (188)

Metabolic regulation of redox balance in ageing Redox reactions occur throughout the cellular metabolism with the production of a small number of reactive oxygen radicals

Absorption, transport and tissue distribution The seminal identification of a mammalian membrane transporter for ergothioneine by Grundemann and colleagues in 2005 (Reference Grndemann, Harlfinger and Golz24) provided a mechanism by which ergothioneine is acquired from the diet, and further evidence for an essential role for ergothioneine in vivo