glutathione s-transferase gsts catalyze the conjugation of the reduced form transferases: substrates, inihibitors and pro-drugs in cancer and neurodegenerative diseases The role of glutathione-S-transferase in

(PubMed) Makhija N, Sendasgupta C, Kiran U, et al

Furthermore, the ATP-dependent conversion of glutamate into glutamine by astrocytic glutamine synthetase turns out to have been impaired during energy failure, thus elevating the intracellular glutamate concentrations in astrocytes, which subsequently leads to reduced glutamate uptake or even enhanced glutamate release by reversed uptake (Lipton and Rosenberg, 1994)

Simultaneously, the body initiated a fibrosis repair process to isolate the lesions that could not be cleared

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