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Discussion The pathways for glutathione synthesis, recycling and metabolism are well established (Figure 6)

Previous research has revealed the upregulation of GLUT1, GLUT3 and GLUT4 in TC, and poorly differentiated types (anaplastic) mainly express high level of GLUT1, while well-differentiated types (follicular and papillary) have stronger GLUT3 and GLUT4 expressions than GLUT1 [43], indicating that the glucose uptake vary by malignant degree

When the amino acid supplementation was changed to one with depleted phenylalanine and tyrosine levels, serum T4 and T3 levels gradually decreased