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Dentists only need to submit a one-time compliance report (See Appendix III), with no ongoing monitoring, meaning 60% of dentists who dont use separators face no consequences

[18] SSRIs, which mainly regulate serotonin, subsequently replaced tricyclics as the primary treatment option for depression because of their better tolerability and lower incidence of adverse effects

Pharmaceuticals 16 , 859 (2023)

Finally, a 2017 Cochrane systematic review and meta-analysis of 20 randomized controlled trials reported a small benefit of omega-3 supplementation on depressive symptoms when compared to placebo, yet the evidence was deemed of very low quality and the positive effect was judged likely to be biased and not clinically significant (195)