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If you are still experiencing significant nausea, vomiting, or diarrhea at the end of a 4-week dose block, stay at the current dose for another 2-4 weeks before attempting the next increase

The most common mild side effects include slight redness or swelling at injection sites, temporary fatigue during the first week of treatment, mild nausea or digestive upset with certain peptides, and temporary water retention, particularly with growth hormone-releasing peptides

Patients with Fitzpatrick IV to VI should consult their dermatologist before starting because of the elevated risk of post-inflammatory hyperpigmentation in darker skin tones

After that, discard and open a new vial