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doi: 10.3389/fphar.2022.845591 Received 30 December 2021 Accepted 21 March 2022 Published 20 May 2022 Volume 13 - 2022 Edited by Fang Pan, Shandong University, China Reviewed by Young-Ji Shiao, National Research Institute of Chinese Medicine, Taiwan George L

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Results clearly showed that the tyrosine-nitration level was reduced in proportion to the molar ratios of GSSSG and LASSS relative to HGF, as revealed by the decrease in anti-nitroY mAb-positive HGF (60-kDa -chain and 90-kDa proform) normalized to total HGF -chain as a loading control, that was monitored by stripping with SDS-ME solution and re-probing the blot with anti-HGF -chain N-terminal domain mAb (Figure 1b,c, second and third rows)