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The hydrophobic residue of the peptide is embedded in the hydrophobic pocket, which enhances the binding stability by van der Waals force and prevents the substrate from sliding into the active cavity (Hu et al., 2022b)

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Grenoble Alpes, Inserm Univ

Accordingly, it provides an in-depth, stepwise account of how cancer cells acquire and catabolize carbohydrates, proteins, and lipids (hereby mostly triglycerides will be addressed) for energy, delineating the routes and control points under well-fed versus fasting states and evaluating where dietary interventions can plausibly constrain these fluxes