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While we are not clear to which other device categories the commenter is referring, we believe there is only one relevant device category code, C1831, we believe the FDA indications are similar and note that both aprevo devices treat many of the same conditions, including degenerative disc disease, deformity (kyphosis or scoliosis), spinal stenosis, and failed previous fusion, at different levels of the spine

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It has been proven that BV inhibits proliferation and causes apoptotic cell death by activating death receptors (DR4 and DR5) (Khaliq et al., 2022)