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FDA-2025-N-6895

For enhancing the precision of the EBRT method, techniques like three-dimensional conformal radiation therapy (3D-CRT) and intensity-modulated radiation therapy (IMRT) with minimal exposure to the surrounding tissues have been developed (210)

149 Charge of K65 (positive charge) in Claudin-1, E158 (negative charge) in Claudin-3, and the polarity of Q56 and Q62 in Claudin-3 and Q57 in Cldn5 are required for establishing tight junction strands