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Description

Journal of Biomaterials Science, Polymer Edition, 19(8), 969988

Neuropathological hallmarks of the disease include the abnormal deposition of amyloid -peptide (A) fibrils, the main component of senile plaques (SPs), and the intracellular accumulation of neurofibrillary tangles (NFTs), composed of hyperphosphorylated Tau protein (pTau)

Further work is needed to better deconvolute the relationship of the PI3K-AKT pathway and TGF- signaling in regulating peripheral versus thymic Treg metabolism