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Multi-systemic effects Beyond sleep, DSIP influences thermoregulation, heart rate, blood pressure, pain threshold, and immune function

Expanding on these data, additional modifications intended to increase hydrophobicity and decrease hydrogen bonding potential yielded N- hexanoic-Tyr-Ile-(6)-aminohexanoic amide (dihexa), a potent cognitive enhancing molecule that proved to be very stable, to be capable of inducing spinogenesis/synaptogenesis at picomolar concentrations, is slowly cleared from the blood compartment, and is sufficiently BBB permeable

For acute applications, like supporting recovery from an injury, this speed is a distinct advantage

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