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Human neurodegenerative disease Friedreichs ataxia results from the deficient of frataxin

Different subtypes have unique sub-cellular localization and functional characteristics: SIRT1 is mainly located in the nucleus and participates in metabolic regulation and inflammatory responses (95, 96)

Crit Care Med 49:e444e453 Geri G, Vignon P, Aubry A, Fedou AL, Charron C, Silva S, Repesse X, Vieillard-Baron A (2019) Cardiovascular clusters in septic shock combining clinical and echocardiographic parameters: a post hoc analysis