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In the study by Saely et al

Its methylation levels are carefully controlled by a ternary writing-erasing-reading regulatory system: writers, also known as methyltransferases, include Wilms tumor 1 associated protein (WTAP), methyltransferase-like 3 (METTL3), and methyltransferase-like 14 (METTL14), which are responsible for installing the m 6 A modification

The AP-1 signaling pathway can be activated by cytokines, growth factors, stress, and bacterial or viral infections, including SARS-CoV proteins ( CCL3 , also reduces its expression in severe COVID-19

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