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Description

Prev Cardiol 2002

7 Respiratory Defense Mechanisms In addition to the cough and sneeze reflexes, two other systems provide the major defense of the respiratory tract against invading organisms or foreign materials: the mucociliary apparatus and the respiratory mononuclear phagocyte system

The latter scenario is the one in PANK-associated neurodegeneration (PKAN), one of the most frequent forms of NBIA (Table 1), in which the alteration of PANK2 impairs coenzyme A (CoA) biosynthesis [13, 142]