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For example, in an in vitro model of Pseudomonas aeruginosa infection of THP-1 macrophages, it was found that quercetin modulated activation of the MAPK pathway and the NLRP3 inflammasome, reducing the release of IL-1 from the cells, and thereby inhibiting the inflammatory response and consequently reducing the invasion of normal cells by pathogens

Calycosin and genistein induce apoptosis by inactivation of HOTAIR/p-Akt signaling pathway in human breast cancer MCF-7 cells