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It includes: - Early gastric lavage after control of seizures and protection of airway - Oral activated charcoal - Supportive treatment: - control seizures with diazepam and or pentothal - correct metabolic acidosis by infusion of sodium bicarbonate solution - manage respiratory failure by oxygen and artificial ventilation - correct hypotension and shock by plasma expanders and/or dopamine - Antidote: administration of pyridoxine

To explore the role of C3aR in NASH fibrosis, MCD mice received C3aR antagonist (SB290157)

The frontier of a potential treatment now lies at the convergence of regenerative medicine and precise gene editing

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