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Furthermore, lactate has emerged as a key player in immune regulation, with evidence pointing to its impact on immune cell function through mechanisms such as receptor signaling via GPR81 and histone lactylation, which are closely linked to its immune-modulatory effects [16]

The C-terminal active site cysteine of Escherichia coli glutaredoxin 1 determines the glutathione specificity of the second step of peptide deglutathionylation

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References Pickart L, Margolina A