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This removal can significantly alter the function of these cells and potentially restore cartilage health, thereby improving joint function and reducing leg pain

There are a host of other peripheral benefits which can be easily observed on a day-to-day basis: Aids in Weight Loss Vitamin B12 facilitates the conversion of fats that we consume through our diet into energy

doi: 10.3389/fphar.2021.604040 Received 08 September 2020 Accepted 05 January 2021 Published 04 March 2021 Volume 12 - 2021 Edited by Jiahong Lu, University of Macau, China Reviewed by Lei Wang, University of Pittsburgh, United States Song-Lin Li, Jiangsu Provincial Hospital of Traditional Chinese Medicine, China Updates Copyright 2021 He, Hu, Li, Zhao, Fan, He, Lu, Ye, Huang and Wu

Clinically, these patterns correspond to the tendency for pain associated with DCM to persist chronically, particularly in the upper extremities (at-level pain) (Siddall and Loeser, 2001