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VIC leads to the inhibition of cell proliferation and growth by generating ROS and altering the expression of genes involved in angiogenesis, glycolysis, and metastasis by regulating the transcriptional activity of hypoxia

indica showed higher POD and CAT activities under NW conditions, suggesting that WS had an inhibitory effect on POD and CAT activities of white clover, which are the main enzymes for H 2 O 2 scavenging (Du et al., 2001)

melanogaster is likely to be fixed in worldwide populations

Later, it was also reported that curculigoside can inhibit osteoclast genesis by reducing ROS generation by means of decreasing the activity of oxidase while activating the NrF2 pathway and suppressing the NF- kB signaling pathway in RAW264.7 cells [96]