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LV-GPX1 was used to increase the exogenous expression of GPX1 in vivo, and LV-Con was used as the control vector

Therefore, it is conceivable that HO inhibition in the brain is not desired, although some have speculated that it may be advantageous in premature infants with intracranial bleeding, where a possibility of enhanced local bilirubin formation exists (Drummond and Kappas, 1986)

Indeed, CT has a net positive charge and an estimated log partition coefficient of -2.7 [13], which would not be consistent with diffusion of CT through plasma membranes

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