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doi: 10.1210/jc.2018-02414 65 ZhangXYeungDCYKarpisekMStejskalDZhouZ-GLiuFet al

We also demonstrated that xCT and GPX4 expression was significantly lower in cultured tubular epithelial cells that were exposed to TGF-1, as well as in the kidneys of diabetic mice, resulting in low glutathione levels and enhanced lipid peroxidation