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During a median follow-up of 27.5 months, lobar ICH events (OR 0.10, p = 0.015), presence of cSS (OR 0.19, p = 0.028), high white matter hyperintensities Fazekas score (OR 0.41, p = 0.007) were negatively associated with favorable outcome after adjustment for age, sex and immunosuppressive treatments

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NOX enzymes are activated by diverse mediators, including PDGF [78], angiotensin II [79], leptin [80, 81], alcohol [82], and phagocytosis of apoptotic hepatocyte bodies [83]

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