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Description

Ozden O, Park SH, Wagner BA, Song HY, Zhu Y, Vassilopoulos A, et al

doi: 10.1152/ajpcell.1997.273.4.C1378

Mechanistic Studies Subsequent research has explored the mechanisms by which NNMT regulates metabolism, with studies demonstrating that NNMT activity reduces cellular NAD+ availability, affects SAM-dependent methylation reactions, modulates sirtuin activity, and influences adipocyte differentiation and function