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Finally, ROX was measured after ROT treatment and subtracted from all conditions to exclude non-mitochondrial oxygen consumption (Fig

The knockdown of endogenous ACSL4 in interleukin (IL)-1-treated rat fibroblastic cells or lipopolysaccharide-treated bone marrow-derived macrophages significantly decreased PC and PI species bearing AA and increased the production of prostaglandin E2 (PGE2), prostaglandin D2, and prostaglandin F2