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doi: 10.3389/fcell.2025.1629762 Received 16 May 2025 Accepted 17 July 2025 Published 20 August 2025 Volume 13 - 2025 Edited by Linhui Zhai, Tongji University, China Reviewed by Xixin He, Guangzhou University of Chinese Medicine, China Gang Chen, Guangdong Pharmaceutical University, China Updates Copyright 2025 Liu, Qi, Feng, Li, Zhong and Bai

e310 Zou Y, Li H, Graham ET, Deik AA, Eaton JK, Wang W, et al

The most advanced methods currently in clinical trials or commercially approved employ indirect targeting by immunotherapies, which focus on immune components required for MYC -driven tumors or checkpoints that are altered in MYC -driven tumors [83, 84]