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Effects of metformin and donepezil on the prevention of doxorubicin-induced cardiotoxicity in breast cancer: a randomized controlled trial

10.1038/aps.2017.110 302 ZhaoP.-Y.JiJ.LiuX.-H.ZhaoH.XueB.JinL.-Y.et al (2020)

As previously mentioned, those with phase three liver injury and signs of progressive organ dysfunction, severe acidosis or multiorgan failure have a poor prognosis and should be referred for possible liver transplantation

Colonic fermentation of these fibers releases short-chain fatty acids that stimulate peristalsis, reinforce mucosal integrity, mitigate low-grade inflammation, and induce glucagon-like peptide-1 (GLP-1) secretion, all of which foster a healthy microbiome and stabilize glucose metabolism