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In rare cases, folate deficiency is associated with megaloblastic anemia and birth defects, especially neural tube defects, in children born to mothers with folate deficiency

Supplements and topical treatments have comparable advantages, but injections frequently produce noticeable effects much more quickly

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Comparison of the short-term results of single-dose intra-articular peptide with hyaluronic acid and platelet-rich plasma injections in knee osteoarthritis: a randomized study. Clinical rheumatology 39.10 (2020): 3057-3064