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For instance, the depletion of GSH, a major cellular antioxidant that is essential for detoxifying ROS and maintaining redox balance within the cell (Akhigbe and Ajayi 2020

Hypoxiainducible factors: coupling glucose metabolism and redox regulation with induction of the breast cancer stem cell phenotype

Gut 66, 429437

2.5 Immune microenvironment With the continuous study of tumor immunity, some researchers have proposed several immune subtypes of tumors based on the histological characteristics of tumors ( Figure 2 )