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Some studies suggest that although the accumulation of ROS plays a key role in the initiation and acceleration of cell death in PD, it is not the only cause of cell death in this disorder [39]

Store the prepared nasal spray in the fridge, upright, for up to six months

Assuming that the gaps opened in the BBB are straight pores of uniform size r g , the size-dependent BBB permeation of nanoparticles can be modeled using the pore-flow model 44,45 , with modification, which has previously been used to model the filtration across biological and artificial membranes (Fig

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