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Chung, W.-H

doi: 10.1016/j.jfutfo.2022.08.006 56

To elucidate the potential association between Paneth cells and the inhibitory effects of ALA on ISC aging, we established a co-culture system utilizing Lgr5 + ISCs and CD24 + Paneth cells (Fig

Oxidative stress and mitochondrial reactive oxygen species The mitochondrial ETC is the major source of intracellular ROS production [72], and mitochondrial dysfunction can lead to increased levels of superoxides, hydrogen peroxide, and hydroxyl radicals [73]