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48,49 It should be noted that medications studied for treatment of neuropathic pain including gabapentin, pregabalin, nortriptyline, and duloxetine have not been shown to have a significant effect on muscle cramps in clinical studies

-Superoxide dismutase (SOD) activity: SOD is an enzyme that catalyzes the dismutation of the superoxide radical into ordinary molecular oxygen and hydrogen peroxide

Gegen Qinlian decoction ameliorates insulin resistance in type 2 diabetes: A systematic review and meta-analysis of RCTs with mechanistic insights into SIRT1/AMPK pathway activation