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However, the low degree of inhibition demonstrated by the extract suggested that this type of pathway was not primarily involved in the vasodilation process

doi: 10.1073/pnas.1603244113 16 XuTDingWJiXAoXLiuYYuWet al

Speech can be either high-pitched (Minnie Mouse-esque), or low pitched and hoarse, there may be occasional diplophonia (two vocal tones), and patients may activate accessory facial, tongue and chest wall movements in the struggling production of effortful speech (107)