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508 In the field of international studies, various scoring systems such as the gut microbiota score, HCT-CI score, and DeltaAlb0.9 have been utilized to assess the likelihood of developing grade III-IV aGVHD

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Since mitochondria replicate their DNA independently of the cell cycle, there is a greater chance of these replication errors occurring [8]

In vivo studies using two-photon fluorescence lifetime imaging and genetically encoded sensors (e.g., the laconic lactate biosensor) have confirmed that astrocytes generate lactate via glycolysis during neuronal activation, which is transported to neurons through monocarboxylate transporter MCT2