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In several studies, supplementation with carnitine was shown to improve constipation challenges

Bio-stimulants have emerged as alternatives to chemical inputs, and promising approach to enhance crop growth, yield and, quality with less environmental damage 10

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Crucially, the selective deletion of mutant SOD1 specifically from astrocytes was shown to slow disease progression and extend the lifespan of these models, confirming the critical pathogenic role of astrocytes in ALS [314,323]