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The potential intrinsic distortion and the noise floor were examined by recording the sound in the coupler to which the primary tones were presented at the maximal level (80 dB SPL) for DPOAE test

This finding supports the safety of APE at therapeutic doses, making it a promising candidate for further exploration in anti-inflammatory and antioxidant therapies

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Lifestyle interventions should prioritize weight loss through dietary modificationsparticularly reducing the intake of high-fat and high-sugar foodsand regular physical activity and the strict avoidance of alcohol due to its adverse impact on lipid metabolism