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GPX4 is an antioxidant enzyme that primarily reduces lipid peroxides, especially lipid hydroperoxides, into their corresponding alcohols, thus protecting cell membranes from oxidative damage [39]

Over the past few decades, various diagnostic frameworks have been established, with the most widely adopted being the 1990 National Institutes of Health (NIH) criteria, the 2003 Rotterdam Consensus, and the 2006 Androgen Excess and PCOS Society (AES) criteria

Oxidative stress: impact in redox biology and medicine

EAAC1 is tightly regulated by molecules, including glutamate transporter-associated protein 318 (GTRAP3-18) and miR-96-5p, offering potential therapeutic targets to optimize neuronal GSH levels and mitigate early neurodegeneration (6)