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Histamine intolerance (HIT / adverse reactions to ingested histamine): A suggested non-IgE pathology is a defective capacity to degrade histamine, frequently by way of the reduced histamine degradation capacity, intestinal DAO deficiency, or impaired methylation resulting in the histamine buildup and multi-system often unspecialized symptoms

Kim DW, Tan EY, Jin Y et al , Effects of imatinib mesylate on the pharmacokinetics of paracetamol (acetaminophen) in Korean patients with chronic myelogenous leukaemia

Because of the redox activity of the labile iron pool, it is thought to contribute to oxidative stress during iron overload (Piloni et al., 2016[345])