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Figure 2 Reduction of Covid-19 Comorbidity Risk by TPS In a retrospective study of 1,591 severely ill patients with COVID-19, hypertension was the most common comorbidity (49%), followed by cardiovascular disease (21%), hypercholesterolemia (18%), and diabetes (17%) ( Pulmonary Fibrosis COVID-19 patients may have the sequelae of pulmonary fibrosis, with symptoms such as dry cough, fatigue, and dyspnea, leading to weight loss, worsening physical condition, long-term disability, and affecting the patient's quality of life ( During treatment of pulmonary fibrotic rats with EGCG, the rats exhibited reduced inflammation, alveolar damage, and vascular congestion, which were associated with the membrane-stabilizing and antioxidant properties of EGCG, demonstrating that EGCG can act as a potential anti-fibrotic drug ( Diabetes High-risk patients with severe COVID-19 or death have a variety of characteristics, including advanced age and masculinity, as well as potential health problems such as cardiovascular disease, obesity, and diabetes ( Drinking 34 cups of tea per day (600900 mg/day) is often considered to prevent personal obesity metabolic syndrome or reduce disease risk ( Depression In addition to posing a significant threat to physical health, the COVID-19 pandemic also poses a threat to the population's mental health due to increased fear and uncertainty

DNA methyltransferases (DNMTs), including DNMT1, DNMT3A, and DNMT3B, catalyze DNA methylation process

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