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Biological Functions of GPX4 in the Regulation of Pain Antioxidant Defense GPX4 plays a crucial role in regulating oxidative stress by acting as an essential antioxidant enzyme that protects cells

Interestingly, vitamin E has recently been reported to have another possible function - direct inhibition of lipoxygenases, which may be achieved by competing for the substrate binding site with lipoxygenases (Kagan et al., 2017)

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