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In some embodiments, Lipid Nanoparticles (LNPs) are formulated to encapsulate a pharmaceutical agent (e.g., siRNA) using a spontaneous vesicle formation formulation procedure, as previously described in Semple et al (2010) nat

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In studies of trauma patients, serum levels of IL-6, IL-10 and serum endothelial-selectin were all increased in patients with a history of alcohol abuse on admission to the ICU when compared to non-alcoholics