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In that phase, there is little perceived need or appetite, literally or psychologically, to engage with nutrition beyond eating less

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However, only a small percentage of patients ( 1%) achieve the desired endpoint of functional cure, defined as the loss of hepatitis B surface antigen (HBsAg) and HBV DNA below the level of quantitation, that permits safe discontinuation of therapy [4, 5]

Keith DE, Murray SR, Zaki PA, Chu PC, Lissin DV, Kang L, Evans CJ, von Zastrow M: Morphine activates opioid receptors without causing their rapid internalization