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Large extraparenchymal arteries, including the vessels of the circle of Willis and major pial arteries, possess a well-developed tunica media with multiple layers of smooth muscle (ranging from 20 layers in the internal carotid artery to 23 layers in smaller pial arteries) and a prominent internal elastic lamina ( Penetrating arterioles, which branch from pial vessels within the Virchow-Robin space, exhibit fewer layers of smooth muscle and reduced elastic structures, marking the transition toward greater local control ( 2 and K + and play a larger role in NVC and CVR

10.3390/biomedicines9081073 130 PernaA.HayE.SellittoC.Del GenioE.De FalcoM.GuerraG.et al (2023)

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(2006) compared different groups of RAW 264.7 cell line murine macrophages that treated with diallyl trisulfide, diallyl disulfide, and diallyl sulfide, respectively