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Additionally, patients could worsen during the study and still be classified as recovered and the study was unblinded with subjective outcomes

The procedure first focuses on fixing any impingement causing bone deformities

Alexander, A., Patel, R

Since the focus of this study is to investigate how UDP-Gal ligand and metal ion cofactor binding influence the structural stabilization of these domains rather than to observe conformational transitions, conventional MD simulations are sufficient to capture the relevant dynamics