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320 Targeted ligands, such as proteins, antibodies, peptides, nucleic acids and chemical small molecules, can be modified on the surface of MSNs, and the modified MSNs are capable of selectively aggregating at the lesion site based on the strong affinity between the targeted ligands and the specific receptors overexpressed in the disease microenvironment

Firstly, the glycolytic intermediate 3-PG is oxidized to 3-phosphohydroxypyruvate (3-PHP) through the action of PHGDH, coupled with NAD reduction to NADH

J., Bonar, F

Phosphodiesterase-5 Inhibition Alleviates Pulmonary Hypertension and Basal Lamina Thickening in Rats Challenged by Chronic Hypoxia