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Lee et al (157) reported that the cytosolic iron chaperone poly(rC)-binding protein 1 (PCBP1) negatively regulates ferroptosis by inhibiting lipid synthesis and peroxidation, and that excessive iron accumulation leads to mitochondrial dysfunction in PCBP1-inhibited cells

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haematobium , it is possible that these cathepsins are an evolutionarily older mechanism of facilitating penetration into a wider variety of hosts